Caroline Wozniacki fought back from a stuttering start to run away with a three set success over Svetlana Kuznetsova.
The 135-minute contest began with Russian Kuznetsova soaring away in the opening tie-break to put Wozniacki on the back foot.
The Dane, undoubtedly the most popular figure to grace Devonshire Park since she lifted the Eastbourne crown in 2009, played tentatively but pulled off some big shots to level matters.
The third set was a one-sided affair, Kuznetsova’s game falling apart with some wayward shots and producing unforced errors.
This gave Wozniacki the edge and she lifted her game to overcome her opponent 6-7(4) 6-3 6-1. Wozniacki faces #10 seed Andrea Petkovic in the quarter-final.
Wozniacki, the #2 seed, lost concentration during the opening set and allowed her 5-1 lead to slip.
Kuznetsova took advantage of the Dane’s nerves to collect five of the next six games to force a tie-break, saving a set point in the 12th game.
There was no stopping the Russian, who stormed into an unassailable lead to set up six set points before seizing the set with an ace on her fourth opportunity.
Wozniacki’s fightback secured the second set and having found her groove the ex-world #1 stormed into a final set 5-1 lead before grasping victory.
Number 2 seed Wozniacki, who gave a good account of herself against the former Eastbourne, French Open and US Open champion, said: “I was 5-1 up in that first set, so when I was 5-1 up in the third set I was thinking that I really couldn’t repeat what happened earlier.
“I served better as the match went on and tried to take the ball a little earlier, which gave me the edge. But the only thing that really matters is to get the win.”
Wozniacki’s quarter-final opponent is #10 seed Andrea Petkovic from Germany, who despatched American CoCo Vandeweghe 6-3 6-4.